Cushing’s syndrome has general symptoms that are similar to several other health conditions and, as a result, it can be difficult to diagnose. Several polymorphisms in the gene coding for the glucocorticoid receptor have been described and these may contribute considerably to the observed variability in glucocorticoid sensitivity. Treatment of Cushing's syndrome is essential to reduce mortality and associated comorbidities. It also includes the normalization of comorbidities via directly treating the cause of Cushing's syndrome and by adjunctive treatments (eg, antihypertensives). It is … It helps with a number of your …

Cushing's syndrome (CS) is the state of hypercortisolism that results from endogenous or exogenous glucocorticoid excess. Cushing’s syndrome is a collective name for a number of endocrine conditions associated with the overproduction of cortisol by the adrenal gland. Equine Cushing's Disease Equine Cushing's Disease is a condition of older horses and typically develops in horses over 15 years of age, although it can develop in younger animals. The latter term is technically incorrect because it is now known that the disease is different from human Cushing’s disease. Causes of Cushing’s(cont.) Cushing’s syndrome can lead to high blood glucose, so try not to eat foods that can cause a rise in blood sugar. Introduction. Cushing's disease, or pituitary ACTH dependent Cushing's syndrome, is a rare disease responsible for increased morbidity and mortality. The symptoms and signs of Cushing’s syndrome result directly from chronic exposure to excess glucocorticoids. Cushing’s syndrome is caused by chronic exposure to excess cortisol. disease commonly known as equine Cushing’s disease. Cushing’s syndrome is caused by an excess of the hormone cortisol. Causes of Cushing’s Majority of the people who suffer from Cushing’s syndrome have had prior use of glucocorticoid hormones -Glucocorticoid hormones are used to prevent transplant rejection as well as treat inflammatory diseases such as asthma, rheumatoid arthritis and lupus 5. Most actions of glucocorticoids are mediated by the glucocorticoid receptor. Academia.edu is a platform for academics to share research papers. Cushing’s syndrome affects about three times as many women as men. Effective treatment includes the normalization of cortisol levels or action. Cortisol production is controlled by the secretion of adrenocorticotrophic hormone (ACTH) from the pituitary and is under negative feedback control from cortisol. Your adrenal glands produce cortisol..