Alcohol Dehydrogenase Pathway. Western blot analysis with Rocklands Anti-Alcohol Dehydrogenase antibody was used to detect yeast Alcohol Dehydrogenase. cytosol, nucleoplasm, plasma membrane, alcohol dehydrogenase activity, zinc-dependent, retinol dehydrogenase activity, zinc ion binding, alcohol metabolic process, drug metabolic process, ethanol oxidation, retinoic acid metabolic process Maximum rates … Comparison to molecular weight markers (not shown) indicates estimated molecular weights consistent with monomer, dimer and tetramer present in this preparation. But, alcohol dehydrogenase breaks alcohol down to another toxic compound, acetaldehyde. For detailed information about alcohol dehydrogenase, go to the full flat file. Acetaldehyde is a well known toxin and a carcinogen so the …

The alcohol is converted to acetaldehyde, an even more toxic molecule, which is then quickly converted into acetate and other molecules that are easily utilized by our cells. Alcohol dehydrogenases (EC 1.1.1.1) are enzymes that catalyze the reduction of aldehydes and ketones to primary and secondary alcohols, respectively. Thus, a potentially dangerous molecule is converted, through alcohol dehydrogenase, into a mere foodstuff. The molecular weight of the enzymes were estimated by the elution volumes from a Sephadex G-100 column and were found to be about 43,000 (isoenzyme 1) and 69,000 (isoenzyme 2).
The reaction takes place in several places in the body, but mostly in the stomach and liver. The Molecular Weight of Horse Liver Alcohol Dehydrogenase , Acta Chem Scand 12, 465, 1958 • Eklund, H.: Coenzyme Binding in Alcohol Dehydrogenase , Biochem Soc Trans 17 , 293, 1989

The cinnamyl alcohol dehydrogenase isoenzymes were partially purified by (NH4)2SO4 fractionation, and column chromatography on DEAE-cellulose, Sephadex G-100, and hydroxyapatite. This is an abbreviated version! Forms and Functions. BRENDA - The Comprehensive Enzyme Information System. 1.1.1.1: alcohol dehydrogenase.